Competencies

The network offers an attractive performance portfolio in the following fields:

Target Identification & Validation

  • Novel targets and science
  • Disease association
  • in vitro- and in-vivo models
  • Change in expression level of target gene (Overexpression / inhibition; tissue-restricted, inducible, reversible expression)

Medicinal Chemistry & Lead Optimization

  • Medicinal chemistry synthesis
  • Hit-to-lead optimization
  • Documentation of API synthesis
  • Virtual drug development

Preclinical Development

  • Formulation
  • Toxicology
  • in-vitro & in-vivo Pharmacokinetics, -dynamics
  • ADME
  • Dosage
  • Molecular Imaging
  • Experimental Pathology & Histopathology
  • Ex-Vivo Pharmacokinetics (PK)
  • In-vitro, in-vivo and ex-vivo models
  • Animal Facilities
  • Development, implementation and evaluation of preclinical studies
  • Comprehensive and Contextual Data Review of animal studies and regulatory documentation and support

Drug Discovery

  • Compounds
  • Assay development and (high-throughput) screening
  • Biomarker identification and validation
  • Computational drug discovery

Drug Targeting & Drug Delivery

  • Medicinal chemistry
  • Ballon cathers
  • Nano-carrier platform
  • In vivo imaging
  • Theranostic approaches

Enabling technologies

  • Bioprocessing
  • Bioinformatics
  • Genetic engineering
  • in vivo imaging

Contact

Please contact us for further information: